Rapacan (Sirolimus)

Last Updated on 16/01/2026

What is Rapacan (Sirolimus)

Rapacan (Sirolimus) is an orally taken prescription-only drug that contains Sirolimus and is primarily used for organ rejection. Organ rejection is a common phenomenon while you undergo an organ transplantation. That time, the immune system of your body rejects the new organ. Rapacan works there to fix the issue, and thus your new organ is slowly adjusted to your body mechanism.

Key uses of Rapacan:

Kidney Transplantation: Used during Kidney transplantation along with some other drugs like corticosteroids and cyclosporine.

LAM: It is also used in the Lymphangioleiomyomatosis, where women specially forms abnormal cell growth and that damages the tissues of the lungs and causes shortage of breath. The disease is very rare and is known as LAM.

Cancer treatment: In some adults, there can be a special type of cancer that cannot be operated on. The type of cancer is known as pecoma. This is an off-label usage of the medication, but often preferred by doctors.

How does it work?

Rapacan inhibits mTOR by binding itself with a protein. The mTOR regulates cell division and the immune system in your body. Hence, the regulation of mTOR will make the lymphocytes inactive and thus suppress your immune system.

Dosage details:

Go through the dosage details very carefully, as it differs with the weight of the patient. The dosage details are also critical, and hence, always take advice about the dosage from your doctor before taking it. The following details are only for information support:

For the rejection of Kidney transplantation:

• If you weigh more than 40kg – Initiate the dosage with 6mg. and then take 2mg of Rapacan once daily.
• In some patients, the daily dosage needed can be more. In such cases, the initial dosage must not be more than 15 mg, and the later dosages should be 5 mg.
• If your kid weighs less than 40 kg – ensure that he/she is more than 13 years of age.
• Dosage for kids is as according to their weight and the surface areas that need protection.
• Initial dosage is 3mg for each sq. metre of the area covered. The next dosages must not be more than 1mg/sq. metre.
• The duration of the dosage will be critically decided by your doctor.

For Lymphangioleiomyomatosis:

• The dosage is only meant for adults (18+ years).
• Dosage is 2mg each day, and that can increase, as your doctor suggests.
• The duration of taking the dosage will be decided by your doctor.

Administering the drug:

• Take the drug at the same time each day so that your body mechanism adjusts with the immunity faster.
• Regular blood testing is essential as it will show the right dosage for Rapacan. The doctor will alternate the dosage according to the blood report.
• Never take alcohol, grape juices, or anything that can be toxic to you during the medication.

Common Side effects:

Some of the common side effects are:

• Abdominal pain
• Headache
• Edema
• Diarrhoea
• Chances of more infection

Some critical side effects:

Rapacan can form some critical side effects, too:

• Mouth sores or stomatitis.
• Edema or swelling of the limbs
• Increased cholesterol and triglycerides.
• Wound healing seed will be reduced
• Anaemia
• Proteinuria or other kidney issues.

FAQs

Q. Can I take Rapacan with food?

Yes, you can take it with food and can take it without food, too. However, the most important thing here is the continuity. Whatever you do on the first day, continue it every day.

Q. Does Rapacan affect our skin?

Yes, it makes your skin responsive. Hence, you will face issues with sunlight.

Q. How quickly can I expect healing of my wounds?

Your wound healing will be delayed, as the immune system will be delayed with the intake of the drug. You must be careful with the wounds. Try to be safe from them.

Q. What preexisting conditions can cause issues with Rapacan?

If you have prior issues like diabetes or cholesterol, you must disclose that to your doctor. In case of liver issues, too, disclose the same to your doctor.

Q. Can I take the drug during pregnancy?

Yes, you can take, but there is ample need for protection. The protection of the same must continue for 12 months on and before taking the pills.

Q. How long does the medication usually continue?

The medication with Rapacan continues for a long time. It can extend till 2-3 years.

Q. Where to get Rapacan pills?

You can obtain Rapacan pills from Powpills, the online generic drug store. You will need a prescription for the purchase.

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