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Ivermectin: Clinical Trials and Case Studies
Ivermectin: A Comprehensive Study
Ivermectin is a type of medicinal substance that is used in the making of different branded medicines. Because of its strong action against parasites, any pill with this substance in it is helpful to get rid of many forms of parasitic infections.
Ivermectin clinical trials and case studies show that it is useful to get rid of infections that occur because of hookworms, roundworms, tapeworms, and so on.
Along with this, it can cure other infection types like onchocerciasis, river blindness, and strongyloidiasis.
You should get to the doctor before using any of its brands, as you need a prescription to buy and use this pill. In addition, going to the doctor also helps figure out your dose, know about risks and how to avoid them with the safety tips, and so on.
How Does Ivermectin Work?
Ivermectin has a strong action on parasites and can kill the worms within a few days if you keep taking the doses on time. Therefore, what it does is to stop the reproduction of these worms, which helps to keep a check on the spread of the infection.
Along with this, studies show that it can stop a few metabolic functions of the parasites, and because of this, the parasites cannot live too long and eventually die.
How Is Ivermectin Used?
Since you have to cure an infection, it is only a good idea to take this medicine at least once a day. Depending on the dose you are taking, a doctor may tell you to use the pill only once a day.
However, in case it is a severe issue of parasitic infection the doctors may tell you to use it up to two or three times a day.
Could There Be Any Harm From Taking Ivermectin?
| 💡 To find out about the long-term use of Ivermectin and its possible side effects scientists did a study. In this study, it was found that the following set of patients had ended with side effects- |
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| ➯ Hence, we do not suggest you use the medicine if you have any of the given issues above. In this case, it is always better to take the advice of a doctor first before starting a dose. |
How Should I Take Ivermectin?
Ivermectin comes in many forms like-
- Orally swallowing tablets
- Dissolving pills
The pills that are swallowed are mostly given to adults who are at least 12 years old and above. The dissolving pills are better for your child when they are below the age of 10. A doctor may tell you to use this medicine even in children but not below 6 years old.
Cost Analysis
As per cost estimates of Ivermectin brands, they vary depending on the countries in which it is available. Even there were state-wise drug rules that changed the pricing of the medicine.
When Can I Take Ivermectin Safe?
Taking Ivermectin has many safety criteria. Here is when it is safe to use Ivermectin.
- In cases when the patient does not have any allergic triggers to the medicinal substance.
- In those cases, the age of the patient is within the criteria of using the medicine.
- When the patient does not have a major liver or kidney disorder like cancer, kidney failure, liver transplant, or any other health issues.
The doctor will likely check the medical history of the patient as well before telling them to use this medicine. In case it is found that the patient has a major heart issue or high BP and has been using medicines to get rid of chest pain and heart attack it may not be safe to take this pill.
Side Effects
Now, it is time for us to check out what sort of side effects may occur with the use of such a pill. As per Ivermectin clinical trials and case studies, it has been found that the issues can go from bad to worse and be mild or very severe, but it is rare.
1- Common Side Effects Of Ivermectin
Here is a list of the common issues that can occur with the use of this pill-
Most of these mild issues are cured on their own and go away within a couple of days. In case it does not then you need to contact the doctors to reduce your dose.
2- Serious Side Effects Of Ivermectin
It is very rare to see some serious side effects of the medicine as it has been found to occur in less than 1% of patients. Here is a list of some of the severe issues.
- Severe headache
- Severe weight loss
- Bloody diarrhea
- Allergic triggers that cause inflammation, redness, and itching on the face, lips, and skin around the body
In case any of these issues occur, it is a good idea to stop using the medicine. In general, such severe side effects can only occur when interaction with other pills occurs, or else with alcohol.
Sometimes allergic triggers occur when the patient is not able to tolerate the action of the medicine.
How is Ivermectin Supplied (Dosage Forms)?
The dosage of Ivermectin generally comes in three different dose variants such as-
It depends on how severe the issue is and what the condition being treated for to find out the exact dose. A doctor will also check the age and health of the patient to find out a suitable dose.
How Should I Tell My Healthcare Provider Before Taking Ivermectin?
Get to the doctor and first tell you about the symptoms that you have been having for the last few days. Based on the symptoms it may be possible to find out if your infection needs the use of Ivermectin for the perfect cure. To find out more, the doctors may want you to go through blood tests, urine tests, skin tests, and so on.
| 📦 How Should I Store Ivermectin? |
| ❯❯ To store Ivermectin is not hard at home, as it does not need any special medicated conditions. You can easily store it in normal room temperature conditions but beware of high humid conditions, as it is not safe to store the sachet of pills in such places. |
| ❯❯ For example, it is not a good idea to store the sachet in the kitchen or the bathroom as the high humidity can turn the pills soggy and wet. |
| ❯❯ You do not even need a fridge to store the medicine. However, to keep it safe, you need to ensure any place that does not come within the reach of children. |
📝 Interactions
Here is a list of some substances and drugs that may interact with this pill-
Ivermectin clinical trials and case studies show that it is possible to interact with alcohol and narcotic drugs, and hence such substances are banned from use.
Here is a list of drugs that may not be safe when you are using Ivermectin pills-
Warnings & Precautions
Here is a list of some warnings and tips to follow-
- If using the medicine makes you feel dizzy or have a headache, it is not a good idea to drive a car in such conditions.
- It is also not safe to be pregnant, especially in the last few months while taking this medicine.
- You can consult the doctors if you are a breastfeeding mother.
Comparative Analysis
As per analysis, of different case studies and trials so far Ivermectin was found to be a strong generic medicine that helps get rid of different parasitic infections.
Warnings & Precautions
Here is a list of some warnings and tips to follow-
- If using the medicine makes you feel dizzy or have a headache, it is not a good idea to drive a car in such conditions.
- It is also not safe to be pregnant, especially in the last few months while taking this medicine.
- You can consult the doctors if you are a breastfeeding mother.
Global Sales
Ivermectin now sells globally, after its FDA approval. You can find its many brand names in any country.
Sources:
https://clinicaltrials.gov/study/NCT04891250?cond=Ivermectin&rank=3